Publications

Chakrabarti, S.*, Paek, A. L.*, Reyes, J., Lasick, K. A., Lahav, G., & Michor, F. (2018). Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages. Nature communications9(1), 5372. * These authors contributed equally https://doi.org/10.1038/s41467-018-07788-5

Islam, S., Paek, A. L., Hammer, M., Rangarajan, S., Ruijtenbeek, R., Cooke, L., … & Mahadevan, D. (2018). Drug-induced aneuploidy and polyploidy is a mechanism of disease relapse in MYC/BCL2-addicted diffuse large B-cell lymphoma. Oncotargethttps://doi.org/10.18632/oncotarget.26251

Ballweg, R., Paek A.L. and Tongli Zhang. (2017) A dynamical framework for complex fractional killing. Scientific Reports. 10.1038/s41598-017-07422-2

Paek A.L., Liu J.C., Loewer A., Forrester W.C. and Lahav G. (2016) Cell-to-cell variation in p53 dynamics leads to fractional killing. Cell 165: 631-642. http://dx.doi.org/10.1016/j.cell.2016.03.025

U’Ren, J. M., Wisecaver, J. H., Paek, A. L., Dunn, B. L., & Hurwitz, B. L. (2015) Draft Genome Sequence of the Ale-Fermenting Saccharomyces cerevisiae Strain GSY2239. Genome announcements, 3(4). DOI:10.1128/genomeA.00776-15

Carr A.M., Paek A.L., Weinert T. (2011) DNA replication: failures and inverted fusions. Seminars in Cell & Developmental Biology. 22:866-874. DOI:10.1016/j.semcdb.2011.10.008

Paek A.L. and Weinert T. (2010) Choreography of the 9-1-1 checkpoint complex: DDK puts a check on the checkpoints. Molecular Cell. 40:505-506.  DOI:10.1016/j.molcel.2010.11.015

Kaochar S., Paek A.L., Weinert T. (2010) Replication error amplified. Science. 329:911-913.  DOI:10.1126/science.1194261

Paek A.L., Jones H., Kaochar S., Weinert T. (2010) The role of replication bypass pathways in dicentric chromosome formation in budding yeast. Genetics186:1161-1173. DOI:10.1534/genetics.110.122663

Paek A.L.*, Kaochar S.*, Jones H., Elezaby A., Shanks L., Weinert T. (2009) Fusion of nearby inverted repeats by a replication-based mechanism leads to formation of dicentric and acentric chromosomes that cause genome instability in budding yeast. Genes and Development. 23: 2861-2875. DOI:10.1101/gad.1862709 * These authors contributed equally

Weinert T., Kaochar S., Jones H., Paek A., Clark A.J. (2009) The replication fork’s five degrees of freedom, their failure and genome rearrangements. Current Opinion in Cell Biology. 21: 778-784.  DOI:10.1016/j.ceb.2009.10.004

Bolusani S., Ma C.H., Paek A., Konieczka J.H., Jayaram M., Voziyanov Y. (2006) Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites. Nucleic Acids Research. 34: 5259-5269. DOI:10.1093/nar/gkl548

Ghosh S.K., Hajra S., Paek A., Jayaram M. (2006) Mechanisms for Chromosome and Plasmid Segregation. Annual Review of Biochemistry.  75: 211-241. DOI:10.1146/annurev.biochem.75.101304.124037

Konieczka J.H., Paek A., Jayaram M., Voziyanov Y. (2004) Recombination of hybrid target sites by binary combinations of Flp variants: mutations that foster interprotomer collaboration and enlarge substrate tolerance.  Journal of Molecular Biology. 339: 365-378.  DOI:10.1016/j.jmb.2004.03.060